Research progress on genome-wide association studies of colorectal cancer / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 360-366, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-252620
ABSTRACT
Colorectal cancer (CRC), one of the most common malignant tumors, is caused both by environmental and genetic factors. Genetic factor plays an important role in the pathogenesis of CRC. Genome-wide association study (GWAS) is a new tool of genetic research. A series of susceptibility genes and loci of the complex diseases has been identified with GWAS strategy. In this article, the research progress on GWAS of CRC is reviewed, and the advantages and limitations of GWAS study as well as the prospective of its application are discussed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Colorectal Neoplasms
/
Genetic Predisposition to Disease
/
Polymorphism, Single Nucleotide
/
Genome-Wide Association Study
/
Genetics
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2013
Type:
Article
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