Increased level of prostate-specific antigen: a diagnostic marker of hyperandrogenism women / 中华男科学杂志
National Journal of Andrology
;
(12): 1028-1030, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-252837
ABSTRACT
<p><b>OBJECTIVE</b>To determine whether the increased level of serum prostate-specific antigen (PSA) could be used as a diagnostic marker of hyperandrogenism in women.</p><p><b>METHODS</b>Forty-five female patients with hyperandrogenism and 50 healthy control women were detected for the levels of serum PSA, testosterone (T), sex hormone binding globulin (SHBG) and dehydroepiandrosterone sulfate (DHEA-S). The results were statistically analyzed.</p><p><b>RESULTS</b>The level of serum PSA was found to be significantly higher in the hyperandrogenism patients than in the healthy controls (9.72 +/- 1.39 pg/ml vs 3.56 +/- 0.44 pg/ml, P < 0.01), and it showed a weak positive correlation with T (r = 0.226, P < 0.05) and DHEA-S (r = 0.255, P < 0.05), and a weak negative correlation with SHBG (r = -0,228, P < 0.05).</p><p><b>CONCLUSION</b>The increased level of PSA could be used as a diagnostic marker of hyperandrogenism in females.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Sex Hormone-Binding Globulin
/
Body Mass Index
/
Case-Control Studies
/
Prostate-Specific Antigen
/
Hyperandrogenism
/
Diagnosis
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Female
/
Humans
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2009
Type:
Article
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