Study on purification of strictosamide from Nauclea officinalis by macroporous resin / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study on the purification of strictosamide from Nauclea officinalis by macroporous resin to provide reference for production.</p><p><b>METHOD</b>The best macroporous resin was selected among 10 kinds of resins according to adsorption and desorption of the static adsorption experiments. The adsorption quantity, elution volume of water, concentration and elution volume of alcohol were determined according to the single factor experiment.</p><p><b>RESULT</b>HPD400 was the best resin, and the best adsorption quantity was 20.23 mg x g(-1), the elution volume of water and 30% alcohol was 6 BV, and the elution volume of 70% alcohol was 4 BV.</p><p><b>CONCLUSION</b>This technology is simple, feasible, and it can provide reference for the industrialized production.</p>