Effects of pumpkin polysaccharides on blood glucose and blood lipids in diabetic rats / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 358-361, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-253143
ABSTRACT
<p><b>AIM</b>To investigate the effects of pumpkin polysaccharides on blood glucose and lipids levels in diabetic rats.</p><p><b>METHODS</b>Diabetic rats induced by alloxan through intraperitoneal injection were randomly divided into three groups, diabetes, xiaoke pill and pumpkin polysaccharides group, according to weight and blood glucose level. And the normal control group was founded at the same time. The normal control group and diabetes group were lavaged with distilled water, other two groups were respectively lavaged with xiaoke pill or pumpkin polysaccharides. Weighed once a week, and analyzed fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, and free fatty acid level in serum after 4 weeks.</p><p><b>RESULTS</b>In diabetes group, weight and high density lipoprotein level decreased, and fasting blood glucose, total cholesterol, triglyceride, low density lipoprotein, and free fatty acid level in serum increased significantly. But, all of the indexes changed oppositely in xiaoke pill group and pumpkin polysaccharides group, and effects of pumpkin polysaccharides were better.</p><p><b>CONCLUSION</b>Pumpkin polysaccharides can increase the weight, decrease the blood glucose and lipids levels in diabetic rats, and have some good effects to diabetes and diabetes complications.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Polysaccharides
/
Blood
/
Blood Glucose
/
Chemistry
/
Rats, Wistar
/
Cucurbita
/
Diabetes Mellitus, Experimental
/
Hypoglycemic Agents
/
Lipids
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Applied Physiology
Year:
2006
Type:
Article
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