Experimental studies on antiarrhythmic effect of jumi extraction / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 399-402, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-253393
ABSTRACT
<p><b>AIM</b>To investigate the antiarrhythmic effect of jumi (JM) extraction.</p><p><b>METHODS</b>The conventional antiarrhythmic methods were used.</p><p><b>RESULTS</b>Administration of JM extraction reduced the occurrence of ventricular fibrillation induced by chloroform in a dose-dependent manner in mice. Quinidine significantly decreased the number of ventricular premature beats and ventricular tachycardia, shortened the duration of arrhythmia in aconitine-treated rats. But JM extraction had no effect on aconitine-induced arrhythmia. Compared with control, arrhythmia score was lower in ischemia/reperfusion rats which pretreated with 2.0 g/kg of JM extraction.</p><p><b>CONCLUSION</b>JM extraction has obvious protection effects in chloroform- and ischemia-induced arrhythmia, but has no effect in aconitine-induced arrhythmia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arrhythmias, Cardiac
/
Plant Extracts
/
Rats, Sprague-Dawley
/
Therapeutic Uses
/
Drug Therapy
/
Anti-Arrhythmia Agents
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Applied Physiology
Year:
2007
Type:
Article
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