Infection of human papillomavirus in oral benign epithelial proliferation in children / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 426-428, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-253682
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the presence of HPV infection of oral mucosa proliferative lesions in children and determine the associations of HPV types with oral mucosa lesions in children.</p><p><b>METHODS</b>Immunohistochemical method and in situ hybridization techniques were applied to detect human papillomavirus (HPV) infection in biopsies taken from clinical lesions in oral mucosa of 30 children.</p><p><b>RESULTS</b>The most frequent lesions detected were SCP (66.7%), followed by CA and FEH. The HPV viral antigen was present in 73.3% (22/30) of the oral benign epithelial proliferative lesions in children. A high frequency HPV was found in CA (6/6) and SCP (15/20) by means of IHC. In the ISH positive case, high risk HPV 16/18 was observed in 77.3% (17/22).</p><p><b>CONCLUSION</b>This study demonstrates a high prevalence of HPV infection in children's oral mucosa proliferative lesions, and high-risk HPV16/18 are predominant in children's oral mucosa proliferative lesions.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papilloma
/
Papillomaviridae
/
Virology
/
DNA, Viral
/
Immunohistochemistry
/
Condylomata Acuminata
/
Focal Epithelial Hyperplasia
/
Mouth Mucosa
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS