Testosterone decreases adiponectin levels in female to male transsexuals / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 725-729, 2006.
Article
in English
| WPRIM
| ID: wpr-253794
ABSTRACT
<p><b>AIM</b>To evaluate the effect of testosterone (T) on adiponectin serum levels in transsexual female patients.</p><p><b>METHODS</b>We measured adiponectin, leptin, luteinizing hormone and follicle stimulating hormone, T, estradiol, lipid profile, biochemical parameters and body composition in 16 transsexual female patients at baseline and after 6 months of T treatment (100 mg Testoviron Depot /10 days, i.m.).</p><p><b>RESULTS</b>Adiponectin levels were 16.9 +/- 7.3 mg/mL at baseline and 13.5 +/- 7.4 mg/mL at month 6 of T treatment (P < 0.05). Leptin and high-density lipoprotein cholesterol decreased significantly, whereas body mass index, waist circumference and lean body mass increased significantly after 6 months of T treatment. No changes in insulin or Homeostasis Model Assessment were detected.</p><p><b>CONCLUSION</b>T can significantly reduce adiponectin serum levels in transsexual female patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Testosterone
/
Transsexualism
/
Blood
/
Body Weight
/
Sex Hormone-Binding Globulin
/
Body Mass Index
/
Adipose Tissue
/
Cholesterol
/
Bodily Secretions
/
Leptin
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Asian Journal of Andrology
Year:
2006
Type:
Article
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