An investigation and analysis on an outbreak of acute gastroenteritis caused by genogroup I and II norovirus / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 263-265, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-254087
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the cause of an outbreak characterized by diarrhea and vomit in a middle school in Huzhou City.</p><p><b>METHODS</b>Comprehensive analysis was conducted based on field epidemiological study, clinical characteristics of the cases and laboratory test.</p><p><b>RESULTS</b>578 cases of acute gastroenteritis were found. The attack rate was 23.58%. The most frequently observed clinical symptoms were diarrhea, vomiting, abdominal pain and nausea. Some few had fever. Most cases had slight clinical symptom with a course from 1 to 3 days. The cases were distributed in every class, showing no phenomenon of clustering. Norovirus were detected in 11 out of 15 stool samples by using RT-PCR. 6 were genogroup II norovirus. 3 were genogroup I norovirus. enogroup I and II norovirus were detected at the same time in 2 stool samples (the same student with 2 tests). Case-control study showed that drinking unheated bottled water was risk factor (OR = 2.46, 95% CI = 1.19-5.23), and had a dose response relation with the disease (chi = 24.8 P < 0.01). The epidemic was controlled soon through isolating patients during treatment, providing boiled water, disinfecting and health education.</p><p><b>CONCLUSION</b>This was an infectious diarrhea outbreak caused by norovirus. The suspected transmission ways were drinking unheated bottled water and contact daily.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virology
/
Water Microbiology
/
Water Supply
/
Case-Control Studies
/
Acute Disease
/
Epidemiology
/
Disease Outbreaks
/
Classification
/
Caliciviridae Infections
/
Norovirus
Type of study:
Observational study
/
Risk factors
Limits:
Adolescent
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2008
Type:
Article
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