Characterization of rabies virus phosphoprotein in high prevalence provinces of China / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 165-167, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-254116
ABSTRACT
<p><b>OBJECTIVE</b>Characterization of rabies virus phosphoprotein through analyzation of genetic variations about rabies virus phosphoproteins in high-incidence regions in China.</p><p><b>METHODS</b>The nucleotide sequence of the P gene of Guangxi, Guizhou and Hunan provinces positive sample's were sequenced, and the P region's similarity and phylogenetic analyses were completed by using softer wares.</p><p><b>RESULTS</b>The similarity of P region's nucleotide sequence is 82.1%-100%, while, the similarity of amino acid sequence is 87.5%-100%. A little variation in phosphoprotein cannot influence its biological functions.</p><p><b>CONCLUSION</b>All rabies viruses isolated from Guangxi, Guizhou and Hunan provinces belong to genotype 1 and share same phylogenesis and same genome characteristic; Virus distribution presents unique Characterization; Some virus isolates from Hunan province and Thailand may come from the same virus.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phosphoproteins
/
Phylogeny
/
Rabies
/
Rabies virus
/
Virology
/
Molecular Sequence Data
/
Viral Structural Proteins
/
China
/
Epidemiology
/
Prevalence
Type of study:
Prevalence study
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2008
Type:
Article
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