Research progress in molecular biology of pediatric myelodysplastic syndrome / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 957-961, 2014.
Article
in Zh
| WPRIM
| ID: wpr-254158
Responsible library:
WPRO
ABSTRACT
Marked differences have been found in molecular characteristics between pediatric and adult myelodysplastic syndrome (MDS) patients. The incidence of gene mutations associated with myeloid malignances in pediatric patients is lower than in adults, while the incidence of aberrant methylation is similar between them. It is also worth noting that novel molecular factors such as mitochondrial DNA mutations may play a role in the pathogenesis of childhood MDS. This article summarizes research advances in molecular biology of pediatric MDS.
Full text:
1
Index:
WPRIM
Main subject:
Myelodysplastic Syndromes
/
DNA, Mitochondrial
/
DNA Methylation
/
Genetics
/
Mutation
Limits:
Child
/
Humans
Language:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2014
Type:
Article