Possible mechanisms of Roux-en-Y gastric bypass treatment for type 2 diabetes mellitus / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 737-740, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-254428
ABSTRACT
Roux-en-Y gastric bypass(RYGB) is a classic procedure for the treatment of type 2 diabetes mellitus (T2DM), but it remains unclear why this procedure works. There might be several mechanisms that RYGB works through to treat T2DM, including calorie restriction and malabsorption, improvement of insulin resistance and β-cell functions, and altered secretion of gastrointestinal hormones. Altered levels of adipokines and serum bile acids might also play a role after RYGB. Future researches should concentrate on the exact mechanism of the altered hormone levels after RYGB, and whether different methods of gastrointestinal tract reconstruction could lead to various hormone levels.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
General Surgery
/
Insulin Resistance
/
Gastric Bypass
/
Caloric Restriction
/
Diabetes Mellitus, Type 2
/
Insulin-Secreting Cells
/
Gastrointestinal Hormones
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2014
Type:
Article
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