Your browser doesn't support javascript.
loading
A case of anaphylactic reaction to oral cefaclor / 대한내과학회지
Korean Journal of Medicine ; : S882-S884, 2003.
Article in Korean | WPRIM | ID: wpr-25471
ABSTRACT
Antibiotics induced anaphylaxis is one of the most acute and potentially fatal drug-related adverse reactions. Cefaclor, an oral second-generation cephalosporin with a beta lactam ring, is used various infectious diseases of the respiratory tract. Few cases of cefaclor anaphylaxis have been rarely reported. Here we report a case of anaphylactic reaction to cefaclor in a 40-year-old female patient. She developed systemic reaction comprised of generalized hives with itching, vomiting, abdominal pain, and hypotension. She was treated on our ER with intravenous fluids, intravenous diphenhydramine and subcutaneous epinephrine. Since four month ago, she had developed generalized pruritic eruptions with flu-like symptoms. The rash resolved the same day after treated with intravenous diphenhydramine. On detailed history taking for medication, we had known that she received a same prescription containing a cefaclor at every episode. Subsequently we tested the patient with cefaclor and conducted an intradermal skin test and an ELISA to cefaclor-HSA conjugate. She showed a positive response. Cefaclor is widely used for common infections, physicians should anticipate the possibility of anaphylactic reaction treated with this agent, particularly in cases of multiple exposure.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pruritus / Respiratory System / Urticaria / Vomiting / Immunoglobulin E / Enzyme-Linked Immunosorbent Assay / Skin Tests / Epinephrine / Abdominal Pain / Cefaclor Limits: Adult / Female / Humans Language: Korean Journal: Korean Journal of Medicine Year: 2003 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pruritus / Respiratory System / Urticaria / Vomiting / Immunoglobulin E / Enzyme-Linked Immunosorbent Assay / Skin Tests / Epinephrine / Abdominal Pain / Cefaclor Limits: Adult / Female / Humans Language: Korean Journal: Korean Journal of Medicine Year: 2003 Type: Article