A case of eosinophilic pneumonia under chemotherapy with the combination of 5-fluorouracil and leucovorin for colon cancer / 대한내과학회지
Korean Journal of Medicine
;
: S863-S866, 2003.
Article
in Korean
| WPRIM
| ID: wpr-25475
ABSTRACT
The combination of 5-fluorouracil and leucovorin is the most commonly used chemotherapeutic agents in colon cancer. The most frequent adverse effects include mucositis, diarrhea and myelosuppression. But it has never been reported that eosinophilic pneumonia developed. A 50-year-old woman with a history of colon cancer was treated by chemotherapy with a combination of 5-fluorouracil and leucovorin. Progressive dyspnea and bilateral pulmonary interstitial infiltrates developed. Bronchoscopy with bronchoalveolar lavage confirmed pulmonary eosinophilia. Clinical and radiologic aspects of eosinophilic pneumonia cleared after discontinuation of chemotherapy. We report the first case of eosinophilic pneumonia induced by 5-fluorouacil and leucovorin administration in a patient with colon cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pulmonary Eosinophilia
/
Bronchoscopy
/
Leucovorin
/
Colon
/
Colonic Neoplasms
/
Bronchoalveolar Lavage
/
Diarrhea
/
Drug Therapy
/
Dyspnea
/
Eosinophils
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2003
Type:
Article
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