Long-term survival of high-risk kidney transplant patients / 中华外科杂志
Chinese Journal of Surgery
;
(12): 589-592, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-254752
ABSTRACT
<p><b>OBJECTIVE</b>To summarize the experiences in high-risk renal transplant recipients for ketter long-term survival.</p><p><b>METHODS</b>From April 1991 to December 2008, a total of 921 kidney recipients with high-risk factors were divided into six groups as following (1) pediatric patients (< 18 years old) (GI, n = 34); (2) retransplant recipients (GII, n = 169); (3) high sensitized patients (PRA> 30% or peak PRA > 50%)(GIII, n = 35); (4) elderly recipients (> 60 years old) (GIV, n = 297); (5) diabetic patients (GV, n = 112); (6) patients with HBV/HCV infection or HBV/HCV carrier (GVI, n = 274). Each group was compared to a control of 807 recipients without any above risk factor for patient and graft survival at 1, 3 and 5 years. Incidences of acute rejection (AR), chronic rejection (CR) and complication were analyzed and compared respectively between the studied subjects and the control group as well.</p><p><b>RESULTS</b>Compared with the control group, patient/graft survivals were lower in GII, GIII and GVI (all P < 0.05), GIV had worse patient survival (P < 0.05); AR and CR incidences were greater in GI and GIII (all P < 0.05); GIV, GV and GVI had more complications.</p><p><b>CONCLUSIONS</b>This study suggests the benefits for long-term outcome in high-immunological risk renal transplant recipients of low acute selection incidence rate, and reduction of complication incidences is the key to long term results for non-immunological high risk recipients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Epidemiology
/
Survival Rate
/
Retrospective Studies
/
Risk Factors
/
Kidney Transplantation
/
Treatment Outcome
/
Graft Rejection
/
Graft Survival
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2010
Type:
Article
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