The expression of the estrogen receptor within the mammary gland of the breast hypertrophy and hypogenesis / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the expression of the estrogen receptors(ER) in breast hypertrophy and micromastia.</p><p><b>METHODS</b>The quantity of ER within breast tissue in 13 patients with mammary hypertrophy strictly elected was determined using DCC single dot test. The results were compared with that measured in 13 patients with micromastia.</p><p><b>RESULTS</b>The average of the quantity of the ER was respectively (5.33 +/- 5.70) fmol/mg and (1.17 +/- 0.86) fmol/mg in mammary hypertrophy ground and in the micromastia group. There was obvious significant between the two groups in a statistics basis (P < 0.05) .</p><p><b>CONCLUSIONS</b>The breast hypertrophy is related to the excessive expression of ER within breast tissue,while the micromastia and breast hypotrophy are related to the lower level or the expression inhibition of ER.</p>