Research progress on ubiquitin-specific protease in antiviral immunity / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 578-583, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-255151
ABSTRACT
Ubiquitin-specific protease(USP), which belongs to cysteine protease, is an important member of the deubiquitinating enzyme family(DUB). USP plays an important role in the immune response against viral infections, in which it can regulate the production of type I interferon through various ways to initiate or weaken the antiviral immune response. USP2b, USP3, USP18, USP25, UL36USP and HAUSP play a role of antivirus; while USP4, USP13, USP15 and USP17 negatively regulate antiviral immune response. In this article we review the recent progress on roles of USP family in antiviral immune response.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virus Diseases
/
Interferon Type I
/
Allergy and Immunology
/
Ubiquitin-Specific Proteases
Limits:
Humans
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2015
Type:
Article
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