The value of narrow-band imaging with magnifying endoscopy in diagnosis of early gastric cancer: a meta-analysis / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 435-442, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-255172
ABSTRACT
<p><b>OBJECTIVE</b>To assess the diagnostic value of narrow-band imaging with magnifying endoscopy (NBI-ME) for early gastric cancer (EGC).</p><p><b>METHODS</b>We searched PubMed, Embase, Web of Science and the Cochrane Library for literature of NBI-ME in diagnosis of EGC, and then performed meta-analysis.</p><p><b>RESULTS</b>A total of 12 articles involving 2 278 samples from 2 048 patients were included. The overall sensitivity of NBI-ME for diagnosis of EGC was 0.84 [95% CI 0.80~0.87], specificity was 0.96 (95% CI 0.95~0.97),and area under the symmetric receiver operator characteristic curve (AUC) was 0.9592. The AUC value of the NBI-ME plus conventional white light endoscopy (C-WLE) subgroup (0.9706) was higher than that of NBI-ME alone (0.8162). The incremental yield of NBI-ME plus C-WLE over C-WLE was significant (IY = 9.4%, P = 0.011), while NBI-ME alone over C-WLE was not significant (IY = 0.8%, P = 0.498).</p><p><b>CONCLUSIONS</b>The results show that NBI-ME plus C-WLE is an effective and preferable method for diagnosis of EGC; however, NBI-ME alone is not superior to C-WLE.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Sensitivity and Specificity
/
Gastroscopy
/
Diagnosis
/
Early Detection of Cancer
/
Narrow Band Imaging
/
Methods
Type of study:
Diagnostic study
/
Screening study
/
Systematic reviews
Limits:
Humans
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2015
Type:
Article
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