Cancer Stem Cells in Brain Tumors and Their Lineage Hierarchy
International Journal of Stem Cells
;
: 12-15, 2012.
Article
in English
| WPRIM
| ID: wpr-25527
ABSTRACT
Despite recent advances in the development of novel targeted chemotherapies, the prognosis of malignant glioma remains dismal. The chemo-resistance of this tumor is attributed to tumor heterogeneity. To explain this unique chemo- resistance, the concept of cancer stem cells has been evoked. Cancer stem cells, a subpopulation of whole tumor cells, are now regarded as candidate therapeutic targets. Here, the author reviews and discusses the cancer stem cell concept.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Neoplastic Stem Cells
/
Population Characteristics
/
Brain
/
Brain Neoplasms
/
Glioma
Type of study:
Prognostic study
Language:
English
Journal:
International Journal of Stem Cells
Year:
2012
Type:
Article
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