A preliminary study of beam weight optimization of intensity-modulated radiation therapy with genetic algorithm / 南方医科大学学报

ABSTRACT

<p><b>UNLABELLED</b>To study the method for dose calculation and beam weight optimization of intensity-modulated radiation therapy (IMRT).</p><p><b>METHODS</b>The IMRT dose calculation model based on two-dimensional convolution was constructed, the program of dose calculation and beam weight optimization with genetic algorithm was written with Visual c#.Net, and the optimization results were analyzed.</p><p><b>RESULTS</b>Genetic algorithm optimization of beam weights can produce highly conformal dose distributions within a clinically acceptable computation time.</p><p><b>CONCLUSION</b>Genetic algorithm is valid and efficient in IMRT beam weight optimization, which may facilitate IMRT treatment planning.</p>