Effects of electromagnetic fields of different frequencies on proliferation and DNA damage of gallbladder cancer cells / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To study the effects of low-power electromagnetic fields of different frequencies on proliferation and DNA damage of gallbladder cancer cells.</p><p><b>METHODS</b>The cell growth curve was drawn and single cell gel electrophoresis performed to evaluate the proliferation and DNA damage of gallbladder cancer cells respectively after the cells were exposed to electromagnetic fields of different frequencies.</p><p><b>RESULTS</b>After exposure to low-power electromagnetic fields of different frequencies (0.1-40 MHz), the cells displayed significant changes with obvious cell proliferation inhibition and DNA strand breakage.</p><p><b>CONCLUSION</b>Low-power electromagnetic fields within the range of 0.1-40 MHz may impair the DNA strand and cause inhibition of proliferation of the gallbladder cancer cells, and these effects are related to the frequency of the electromagnetic fields but not in a linear fashion.</p>