Factors influencing the long-term survival in pancreatic carcinoma patients after radical resection / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 870-872, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-255616
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the factors influencing the long-term survival of pancreatic carcinoma patients after radical resection.</p><p><b>METHODS</b>The data of 184 pancreatic carcinoma patients with radical resection were analyzed retrospectively. Analysis of the prognostic factors influencing the long-term survival was performed using Cox proportional hazard regression model.</p><p><b>RESULTS</b>The overall 1-, 3- and 5-year survival rates in this group were 61.7%, 29.0% and 14.3%, respectively. They were 78.0%, 38.4% and 25.7%, respectively, for the patients with a tumor < 3 cm in diameter, significantly better than those with a tumor >or= 3 cm (52.8%, 22.7% and 7.2%, respectively, P < 0.05). Moreover, the 1-, 3- and 5-year survival rates were 67.6%, 30.5% and 17.4%, respectively, in the patients without lymph node involvement, much longer than that in those with lymph node metastasis (37.1%, 20.6% and 0, respectively, P < 0.05). Multivariate analysis by Cox proportional hazard regression model revealed that the tumor size (P < 0.05) and lymph node metastasis (P < 0.01) significantly influenced the long-term survival of the patients.</p><p><b>CONCLUSION</b>Tumor size and lymph node metastasis are significant factors influencing the long-term survival of pancreatic carcinoma patients with radical resection. Therefore, early diagnosis and radical resection are the key points to improve treatment outcome.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreatectomy
/
Pancreatic Neoplasms
/
Pathology
/
General Surgery
/
Adenocarcinoma
/
Proportional Hazards Models
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
/
Chemotherapy, Adjuvant
Type of study:
Observational study
/
Prognostic study
/
Screening study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS