Extramammary Paget's disease of the scrotum: report of 79 cases / 中华肿瘤杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinicopathologic feature and treatment result as well as prognosis of Paget's disease of the scrotum.</p><p><b>METHODS</b>The data of 79 patients with Paget's disease of the scrotum confirmed pathologically from 1993 to 2004 were retrospectively analyzed. The median age of these patients was 62.3 years. The median duration of the disease was 3 years and 7 months. Locally extensive excision and intra-operative frozen section analysis of resection margin were performed in 78 patients. Inguinal and iliac radical lymphadenectomy was done in 7 patients with inguinal lymph node metastasis.</p><p><b>RESULTS</b>Local recurrence developed in 9 patients, and 3 patients died of the disease during follow-up.</p><p><b>CONCLUSION</b>The prognosis of Paget's disease of the scrotum after surgical resection is good. To highly watch out for the disease, to perform histological examination and surgical resection as early as possible are keys to control it successfully.</p>