Analysis of the proteomic changes of the serum of the Smad3 targeted deficient mice / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 452-456, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-256186
ABSTRACT
We have studied the proteomic changes of the serum of the Smad3 targeted deficient mice using 2-DE and PMF approaches. 7 proteins expressed at different level in wild type mice and the Smad3 deficient mice were identified. These results would benefit the research on diagnosis and therapy of osteoarthritis and provided clues to studying the important function of Smad3 mediated TGF-beta signals during the skeletal development.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Peptide Mapping
/
Electrophoresis, Gel, Two-Dimensional
/
Trans-Activators
/
Mice, Knockout
/
Proteome
/
DNA-Binding Proteins
/
Electrophoresis, Polyacrylamide Gel
/
Smad3 Protein
/
Genetics
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2002
Type:
Article
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