Study on the antioxidative effect of Safflor Yellow / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the antioxidative effect of Safflor Yellow (SY).</p><p><b>METHOD</b>Hydroxyl radical scavenge effect of SY was tested with 1,10-phenanthroline-Fe2+ oxidative assay. Lipid peroxidation of mouse liver suspension was measured with thiobarbituric acid colorimetry technique. Hemocytocatheresis was determined with colorimetry.</p><p><b>RESULT</b>Hydroxyl radical could be scavenged by 1.39 to 3.42 g x L(-1) SY dose dependently. Mouse liver suspension peroxidation was inhibited by 77.8 to 776.1 mg x L(-1) SY dosage dependently. Hemocytocatheresis was attenuated by 37.1 to 297.1 mg x L(-1) SY dose dependently.</p><p><b>CONCLUSION</b>SY is an antioxidative part of Carthamus tinctorius.</p>