The expression of EST and ER in hemangioma with its clinical value / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the relationship between estrogen and the development of hemangioma.</p><p><b>METHODS</b>The expression of EST and ER in samples from the thirty-eight cases of hemangioma and six cases of normal control group was examined with the immunohistochemical steptavidin peroxidase conjugated method (SP method).</p><p><b>RESULTS</b>The EST in capillary hemangioma expressed significantly higher than in the cavernous hemangioma, the racemose hemangioma or the control group. Although the EST in cavernous hemangioma and racemose hemangioma also expressed higher than in the control, there are no statistical differences among them. The ER only expressed in some cases in the capillary hemangioma group. No sexual difference was shown in the expressions of the EST and the ER.</p><p><b>CONCLUSION</b>This study shows that there may be a relationship existed between the estrogen and the capillary hemangioma. It may indicate that some capillary hemangioma may be possibly treated by the drugs.</p>