Acute Response to Co-60 Total Body Irradiation (TBI) With 600 cgy at 3 Different Does Rates in the Mice / 대한치료방사선과학회지
Journal of the Korean Society for Therapeutic Radiology
;
: 151-154, 1990.
Article
in English
| WPRIM
| ID: wpr-25659
ABSTRACT
The acute effects of variable dos rates to total body irradiation (TBI) were investigated with 600 cgy of single exposure in the mice as a preclinical model. Total 80 mice (ICR) were used. Twenty of which served as controls, receiving no irradiation. All irradiated mice showed a universal decline in their weight and white blood cell count. The degree of weight loss and leukopenia were similar at 3 different dos rate but slightly prominent with 15 cgy/minute group. The degree of recovery among the groups showed no dose rate dependence. Our results suggest that TBI with 15 cgy/minute may be applicable for clinical therapy with careful evaluation of patient's condition.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Weight Loss
/
Whole-Body Irradiation
/
Leukocyte Count
/
Leukopenia
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Journal of the Korean Society for Therapeutic Radiology
Year:
1990
Type:
Article
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