Effect of laparoscopic colectomy on exfoliated cancer cells in peritoneal cavity and prognosis for patients with colon cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 56-59, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-256818
ABSTRACT
<p><b>OBJECTIVE</b>To assess the effect of laparoscopic colectomy on the exfoliated cancer cells in peritoneal cavity, recurrence and metastasis of patients with colonic carcinoma.</p><p><b>METHODS</b>One hundred and fifty-nine patients with colonic cancer proven by colonoscopy and pathology were divided into two groups based on patient's preference laparoscopic group (n=74) and open group (n=85). The positive rate of exfoliated cancer cells in peritoneal cavity was compared by cytological detection before and after cancer resection. Recurrence, metastasis rate and 3-year survival were compared between the two groups.</p><p><b>RESULTS</b>The positive rates of exfoliated cancer cells in peritoneal cavity were 12.2% (9/74) in the laparoscopic group and 15.3% (13/85) in the open group before cancer resection without significant difference (P=0.718); 20.3% (15/74) and 30.6% (26/85) after cancer resection without significant difference (P=0.138). The follow-up ranged from 4 to 45 months. The 3-year local recurrence rates were 13.6% (8/59) and 8.8% (6/68) (P=0.455), the 3-year distal metastasis rates were 11.9% (7/59) and 17.6% (12/68) (P=0.416) and the 3-year survival rates were 79.7% and 80.0% (P=0.998), and the differences were not statistically significant.</p><p><b>CONCLUSION</b>The laparoscopic operation does not increase the recurrence and metastasis rate and results in similar survival in patients with colonic cancer as compared to open procedure.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Peritoneal Cavity
/
Prognosis
/
General Surgery
/
Survival Rate
/
Laparoscopy
/
Colonic Neoplasms
/
Diagnosis
/
Neoplasm Metastasis
/
Neoplasm Recurrence, Local
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2014
Type:
Article
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