Primitive neuroectodermal tumor/Ewing's sarcoma of the penis in children: a case report and review of the literature / 中华男科学杂志
National Journal of Andrology
; (12): 1115-1118, 2012.
Article
in Zh
| WPRIM
| ID: wpr-256963
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical manifestations, pathological characteristics and treatment of primitive neuroectodermal tumor/Ewing's sarcoma (PNET/EWS) of the penis in children.</p><p><b>METHODS</b>We analyzed the clinical data of a case of PNET/EWS and reviewed relevant literature.</p><p><b>RESULTS</b>The patient was a 5-year-old boy, admitted for penis swelling with pain for 11 months. Biopsy showed a small round cell tumor, CD99 positive by immunohistochemical staining, with EWS translocation by fluorescence in situ hybridization on molecular biological examination. The tumor was confirmed to be PNET/EWS of the penis, and disappeared after 45 weeks of chemotherapy and local radiotherapy.</p><p><b>CONCLUSION</b>PNET/EWS of the penis is an extremely rare disease, with no specific clinical symptoms except penis enlargement with pain. Immunohistochemistry and molecular biological examination contribute to its diagnosis.</p>
Full text:
1
Index:
WPRIM
Main subject:
Penile Neoplasms
/
Sarcoma, Ewing
/
Neuroectodermal Tumors, Primitive, Peripheral
Limits:
Child, preschool
/
Humans
/
Male
Language:
Zh
Journal:
National Journal of Andrology
Year:
2012
Type:
Article