Effects of yijing recipe on sperm apoptosis and mitochondrial membrane potential in patients with idiopathic oligoathenoteratospermia / 中华男科学杂志
National Journal of Andrology
;
(12): 1045-1049, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-256994
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of Yijing Recipe on sperm apoptosis and mitochondrial membrane potential (MMP) in patients with idiopathic oligoathenoteratospermia.</p><p><b>METHODS</b>Using the self-control method, we examined sperm apoptosis and MMP in 30 patients with oligoathenoteratospermia before and after treated with Yijing Recipe.</p><p><b>RESULTS</b>The rates of early sperm apoptosis (AV +/PI -) and MMP loss were significantly reduced after treatment as compared with pre-medication ([2.86 +/- 1.47]% vs [4.26 +/- 2.79]% and [21.77 +/- 13.46]% vs [41.73 +/- 20.30]%, P<0.05). No statistically significant difference was observed in the sperm death rate (PI+) before and after treatment ([34.10 +/- 16.26]% vs [30.21 +/- 13.50]%, P>0.05).</p><p><b>CONCLUSION</b>Yijing Recipe can reduce early sperm apoptosis and improve MMP, which may be one of the mechanisms underlying its efficacy on oligoathenoteratospermia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligospermia
/
Pathology
/
Sperm Motility
/
Spermatozoa
/
Drugs, Chinese Herbal
/
Apoptosis
/
Therapeutic Uses
/
Drug Therapy
/
Asthenozoospermia
/
Membrane Potential, Mitochondrial
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2012
Type:
Article
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