Advances in the mechanisms and early warning indicators of the postoperative cognitive dysfunction after the extracorporeal circulation / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 101-107, 2015.
Article
in English
| WPRIM
| ID: wpr-257674
ABSTRACT
The high incidence of postoperative cognitive dysfunction (POCD) after extracorporeal circulation has seriously affected the prognosis and quality of life. Its mechanism may involve the inflammatory response and oxidative stress,the excessive phosphorylation of tau protein, the decreased blood volume and oxygen in the cerebral cortex. Appropriate early warning indicators of POCD after the extracorporeal circulation should be chosen to facilitate the cross validation of the results obtained different technical approaches and thus promote the early diagnosis and treatment of POCD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Phosphorylation
/
Postoperative Complications
/
Prognosis
/
Quality of Life
/
Cerebral Cortex
/
Tau Proteins
/
Cognition
/
Cognition Disorders
/
Oxidative Stress
Type of study:
Prognostic study
/
Screening study
Limits:
Humans
Language:
English
Journal:
Acta Academiae Medicinae Sinicae
Year:
2015
Type:
Article
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