Research advances in the application of methylprednisolone in the treatment of acute spinal cord injury / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 680-685, 2014.
Article
in English
| WPRIM
| ID: wpr-257694
ABSTRACT
Acute spinal cord injury(ASCI),mainly caused by traffic accidents and fall injuries,is a catastrophic event that can profoundly affect the trajectory of a patient's life. Debate continues over the medical management of ASCI,in particular the usefulness,dosage,and potential risks of methylprednisolone(MP). Although the results of American National Acute Spinal Cord Injury Study 2 and 3 trials led to the wide adoption of a high-dose MP regimen for ASCI patients,the reliabilities of their study methods and data were still questionable. Based on the currently available literature,we conclude that high-dose MP is no longer a recommended therapy for ASCI;however,due to the lack of effective treatment,it remains a useful option for this condition.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spinal Cord Injuries
/
Methylprednisolone
/
Clinical Trials as Topic
/
Treatment Outcome
/
Neuroprotective Agents
/
Therapeutic Uses
/
Drug Therapy
Limits:
Humans
Language:
English
Journal:
Acta Academiae Medicinae Sinicae
Year:
2014
Type:
Article
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