Relation between Beta-2-glycoprotein I and hepatitis B virus surface antigen / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 31-33, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-257894
ABSTRACT
<p><b>OBJECTIVE</b>To clarify the binding character between Beta-2-glycoprotein I (Beta-2-GPI) and HBsAg.</p><p><b>METHODS</b>Beta-2-GPI was purified from human plasma and labelled with biotin. Solid phase enzyme linked absorbance assay was used to investigate its binding with HBsAg.</p><p><b>RESULTS</b>Biotinylated Beta-2-GPI was found to bind HBsAg and the reaction could be inhibited by excess unlabelled Beta-2-GPI.</p><p><b>CONCLUSIONS</b>Beta-2-GPI may play a role in hepatitis B virus infection.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Binding Sites
/
Enzyme-Linked Immunosorbent Assay
/
Glycoproteins
/
Chemistry
/
Hepatitis B virus
/
Biotinylation
/
Beta 2-Glycoprotein I
/
Hepatitis B Surface Antigens
/
Metabolism
/
Methods
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Hepatology
Year:
2002
Type:
Article
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