Aspergillus pneumonia in renal transplant recipients / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 791-794, 2008.
Article
in English
| WPRIM
| ID: wpr-258590
ABSTRACT
<p><b>BACKGROUND</b>Filamentous fungal infections are associated with a high morbidity and mortality in solid organ transplants. The present study aimed to investigate the aspergillus pneumonia in renal transplant recipients, and its diagnosis as well as treatment.</p><p><b>METHODS</b>Approximately 2000 cases of renal transplants were retrospectively studied and we focused on cases hospitalized during August 1, 2005 and February 1, 2007, as the study period. The clinical database and electronic records were analyzed. Recently published literature was reviewed.</p><p><b>RESULTS</b>There was more diabetes and hypertension in the infected group than in the non-infected group (86% vs 62% and 57% vs 39%, respectively). Eighty-six percent of recipients from the infected group had delayed graft function. Seven cases with aspergillus pneumonia were identified based on either fungal culture or radiology. Of the 7 cases, 4 died in a few days after diagnosis. Liposomal amphotericin B was used as a first-line therapy.</p><p><b>CONCLUSIONS</b>Incidences of fungal infection are increasing among renal transplant recipients. Early diagnosis and treatment are critical steps in curing aspergillosis.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Aspergillosis
/
Tomography, X-Ray Computed
/
Retrospective Studies
/
Cohort Studies
/
Kidney Transplantation
/
Diagnosis
/
Drug Therapy
/
Lung Diseases, Fungal
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Screening study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Medical Journal
Year:
2008
Type:
Article
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