Value of 18F-FDG-PET/CT in diagnosis of classic fever of unknown origin / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 174-180, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-259221
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the application of (18)F-FDG PET/CT in diagnosis of classic fever of unknown origin.</p><p><b>METHODS</b>A total of 27 consecutive patients with classic fever of unknown origin (FUO) (19 men, 8 women; aged 24-82 y) underwent (18)F-FDG PET/CT scans. The images were interpreted by visual inspection and semiquantitative analysis(standardized uptake value, SUV). Final diagnosis was based on histopathology or clinical follow-up.</p><p><b>RESULTS</b>The cause of FUO was confirmed by followed investigations in 21 of 27 cases after PET/CT scan, including 10 cases of infection, 4 of noninfectious inflammation, 4 of malignancies and 3 of miscellaneous disorders; and remaining 6 cases were still confirmed FUO. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 100.0 %, 83.3%, 83.3%, 100.0% and 96.3%, respectively.</p><p><b>CONCLUSION</b>For patients with fever of unknown origin, (18)F-FDG-PET/CT can be a sensitive, reliable imaging modality. It is suggested that (18)F-FDG-PET/CT should be considered earlier in detecting the causes of FUO, which is difficultly diagnosed by conventional modalities.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Diagnostic Imaging
/
Tomography, X-Ray Computed
/
Radiopharmaceuticals
/
Fluorodeoxyglucose F18
/
Positron-Emission Tomography
/
Diagnosis
/
Diagnosis, Differential
/
Fever of Unknown Origin
/
Methods
Type of study:
Diagnostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2010
Type:
Article
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