Relationship of polymorphism of SG13S114A/T in ALOX5AP gene with atherosclerotic cerebral infarction / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 630-633, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-259255
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship of the polymorphism of SG13S114A/T in ALOX5AP gene with atherosclerotic cerebral infarction (ACI).</p><p><b>METHODS</b>By polymerase chain reaction and restriction fragment length polymorphism, polymorphism of SG13S114A/T in ALOX5AP gene in 412 cases with ACI and 368 non-ACI controls were analyzed.</p><p><b>RESULT</b>There were no statistically significant differences in the ALOX5AP gene SG13S114 AA genotype and A allele frequencies between ACI group and control group (P>0.05).</p><p><b>CONCLUSION</b>The results do not support genotype SG13S114 A allele as the risk gene for ACI.control group.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Restriction Fragment Length
/
Intracranial Arteriosclerosis
/
Cerebral Infarction
/
Alleles
/
5-Lipoxygenase-Activating Proteins
/
Genetics
/
Genotype
Limits:
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS