Mouse stroke models and strains-related differences in susceptibility to cerebral ischemia / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 541-546, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-259268
ABSTRACT
Mouse stroke models provide experiment basis for study of the mechanisms of cell death and neural repair, and the neuroprotective effect of new drugs. There are at least three models of middle cerebral artery occlusion (MCAO) routinely used in experimental study. These models vary widely in their application in study of cell death or neural repair, and simulation of human diseases. This review article is focused on the characteristics of three mouse MCAO models and the strains-related differences in susceptibility to cerebral ischemia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Species Specificity
/
Brain Ischemia
/
Classification
/
Stroke
/
Infarction, Middle Cerebral Artery
/
Disease Models, Animal
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2009
Type:
Article
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