Risk factors for oncologic outcome after surgical treatment in patients with gastric cancer: a multivariable analysis of 1031 patients / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 115-118, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-259325
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the risk factors for the prognosis in patients with gastric cancer undergoing surgery.</p><p><b>METHODS</b>Clinical data of 1031 cases who underwent gastric cancer resection from January 2003 to December 2007 were studied using univariable analysis and multivariable regression analysis.</p><p><b>RESULTS</b>In 1031 cases,95 (9.2%) cases were early-stage gastric cancer. The other 936 (90.8%) cases were advanced gastric cancer. The tumor was resectable in 980 (95.1%) cases, of which 874 (84.8%) were curative resection,106 (10.3%) were palliative, and 51 (4.9%) were bypass procedures or laparotomy alone. The stage-specific 5-year survival rates were 93.2% (stage IA), 65.1%(stage IB), 52.3% (stage II), 41.4% (stage IIIA), 16.6% (stage IIIB) and 10.6% (stage IV), respectively. The 1-, 3- and 5-year survival rates were 80.2%, 58.0% and 48.2%, respectively. The independent risk factors associated with the prognosis of these patients were tumor size, serum albumin, curative resection, TNM staging and multidisciplinary treatment in both univariable and multivariable analyses.</p><p><b>CONCLUSIONS</b>Early curative resection is the most important treatment for the patients with gastric cancer. Individualized surgical procedure combined with multidisciplinary treatment can improve the outcome. Tumor size, serum albumin level and TNM staging are important predictors of survival in patients with gastric cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Stomach Neoplasms
/
General Surgery
/
Epidemiology
/
Causality
/
Survival Rate
/
Mortality
/
Treatment Outcome
/
Gastrectomy
/
Neoplasm Staging
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2010
Type:
Article
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