Recent progress in vaccines against nicotine addiction / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1189-1194, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-259494
ABSTRACT
Tobacco smoking is a global healthcare problem that poses a substantial and costly health burden. Nicotine is the major constituent responsible for the addiction to tobacco. Current strategies helping tobacco smokers have limited utility in increasing rates of smoking cessation, consequently indicating the need for alternative therapies. A novel therapeutic method is vaccination against nicotine. Nicotine vaccine can generate specific antibodies that can sequester nicotine from cigarette smoke in the blood, and prevent its access to the brain and minimize positive reinforcing effects, which may help smokers to stop smoking. The vaccine will have great potential for the treatment of nicotine addiction and for relapse prevention. Here we will review the current status of vaccines against nicotine addiction and discuss the problems associated with the development of nicotine vaccines.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Tobacco Use Disorder
/
Vaccines
/
Smoking
/
Clinical Trials as Topic
/
Vaccination
/
Smoking Cessation
/
Therapeutic Uses
/
Allergy and Immunology
/
Methods
Limits:
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2013
Type:
Article
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