Progress in the study of BLyS and APRIL on regulating T cell responses in rheumatoid arthritis / 药学学报
Acta Pharmaceutica Sinica
; (12): 979-985, 2013.
Article
in Zh
| WPRIM
| ID: wpr-259520
Responsible library:
WPRO
ABSTRACT
B lymphocyte stimulator (BLyS), a tumor neurosis factor ligand superfamily, is an important factor of B cell survival and activation. However, BLyS also regulates T cell activation and survival, playing key roles in T cell-mediated autoimmune disorders. In the paper, we introduced the mechanisms of BLyS and a proliferation-inducing ligand (APRIL) regulating T cell responses and their roles in rheumatoid arthritis (RA).
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Arthritis, Rheumatoid
/
Recombinant Fusion Proteins
/
B-Lymphocytes
/
Lymphocyte Activation
/
T-Lymphocytes
/
Therapeutic Uses
/
Drug Therapy
/
B-Cell Activating Factor
/
Tumor Necrosis Factor Ligand Superfamily Member 13
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2013
Type:
Article