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Advance in the study of myocardial ischemic preconditioning and postconditioning and the clinical applications / 药学学报
Acta Pharmaceutica Sinica ; (12): 965-970, 2013.
Article in Chinese | WPRIM | ID: wpr-259522
ABSTRACT
Myocardial ischemic preconditioning and postconditioning can reduce myocardial infarct size, improve myocardial contractility, protect coronary endothelial and myocardial cell ultrastructure, as well as reduce the incidence of arrhythmias. Clinical practice has confirmed the safety and efficacy of these two methods of myocardial protection. This paper reviewed about ischemic preconditioning and postconditioning protection mechanisms in myocardial ischemia reperfusion injury and clinical research literatures in recent years, to provide a theoretical basis for finding new treatment strategies on the prevention and treatment of ischemic cardiomyopathy.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Myocardial Reperfusion / Myocardial Reperfusion Injury / Signal Transduction / Myocardial Ischemia / Ischemic Preconditioning, Myocardial / Receptors, G-Protein-Coupled / Ischemic Postconditioning / Methods / Myocardial Infarction Limits: Animals / Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Myocardial Reperfusion / Myocardial Reperfusion Injury / Signal Transduction / Myocardial Ischemia / Ischemic Preconditioning, Myocardial / Receptors, G-Protein-Coupled / Ischemic Postconditioning / Methods / Myocardial Infarction Limits: Animals / Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2013 Type: Article