Research progress on multiple myeloma immunophenotyping and minimal residual disease detected by flow cytometry / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 241-245, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-259607
ABSTRACT
Multiple myeloma (MM) is a haematological malignancy characterized by the accumulation of monoclonal plasma cells in the bone marrow and remained incurable. Flow cytometry has been widely used in the detection of immunophenotype and minimal residual disease, diagnosis, monitoring and prognosis of MM. Normal plasma cells and malignant plasma cells can be distinguished according to different cell surface antigen expression. The clinical significane of many immune markes has been elucidated. However, the clinical significance of some phenotype remains controversial, the detection scheme and gating strategy are not unified. This review discusses the recent research progress on detection of MM immunophenotype and minimal residual disease by flow cytovetry.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Plasma Cells
/
Prognosis
/
Immunophenotyping
/
Neoplasm, Residual
/
Flow Cytometry
/
Multiple Myeloma
/
Antigens, Surface
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2015
Type:
Article
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