A study on hepatic perfusion parameter calculation / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 1250-1253, 2013.
Article
in Zh
| WPRIM
| ID: wpr-259730
Responsible library:
WPRO
ABSTRACT
Hepatic perfusion parameters play an important role in detecting and diagnosing diffusion diseases of liver. Based on a hemodynamic model. In this study, we described a fast and accurate method to calculate the perfusion parameters. First, we used a dual-input one-compartment kinetics model to illustrate the distribution of the contrast agent concentration among the body. Then, we used the Gaussian function to fit the scatter concentration data of portal vein and aorta, to obtain a liver agent concentration on function of time. Finally, we solved the model parameters by using Levenberg-Marquardt algorithm, and calculated the perfusion parameters. The results showed that the method proposed in this study could calculate the parameters precisely, and had a prosperous future application possibility.
Full text:
1
Index:
WPRIM
Main subject:
Perfusion
/
Physiology
/
Algorithms
/
Contrast Media
/
Hemodynamics
/
Liver
/
Models, Biological
Limits:
Humans
Language:
Zh
Journal:
Journal of Biomedical Engineering
Year:
2013
Type:
Article