The effect of PRP and fibrin sealant with the deprotenized bovine bone in the rabbit cranium
Journal of the Korean Association of Oral and Maxillofacial Surgeons
;
: 221-226, 2007.
Article
in Korean
| WPRIM
| ID: wpr-26033
ABSTRACT
PURPOSE:
The purpose of this study is to evaluation of effect on bone formation of PRP and fibrin sealant with deproteinized bovine bone(Bio-Oss) grafts on rabbit cranial defect. MATERIAL ANDMETHODS:
Twelve rabbits were used as experimental animal Two equal 9mm diameter cranial bone defects were created in each rabbit and immediately grafted with Bio-Oss only, Bio-Oss and PRP, and Bio-Oss and Fibrin sealant. Rabbits were sacrificed at 4 and 8 week. The defects were evaluated by histomorphometric analysis.Results:
Kruskal-Wallis tests were performed comparing new bone formation via histomorphometric analysis. No statistically significant difference of new bone formation was found between Bio-Oss only, Bio-Oss and PRP, and Bio-Oss and fibrin sealant at 4 and 8 weeks (P>0.05).CONCLUSION:
This study fails to find a stimulatory effect of PRP and Fibrin sealant on New bone formation of Bio-Oss grafts by histomorphometric analyses.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteogenesis
/
Skull
/
Fibrin
/
Fibrin Tissue Adhesive
/
Transplants
Limits:
Animals
Language:
Korean
Journal:
Journal of the Korean Association of Oral and Maxillofacial Surgeons
Year:
2007
Type:
Article
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