Combined non-biological artificial liver in treatment of late stage chronic severe hepatitis / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 652-654, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-260642
ABSTRACT
<p><b>OBJECTIVE</b>To explore the clinical effects of combined non-biological artificial liver in the treatment of late stage chronic severe hepatitis and especially to observe their effects on hepatic encephalopathy, hepatorenal syndrome and disturbance of electrolytes.</p><p><b>METHODS</b>103 chronic severe hepatitis patients were treated with the same medical measures, including plasma exchange. Among them, 63 patients were also treated with combinations of non-biological artificial liver (treatment group), and the other 40 patients served as controls (control group). The efficacy of the treatments and survival rates of the two groups were compared.</p><p><b>RESULTS</b>In the treatment group, the rate of regaining normal consciousness was 72.7%, the rate of electrolyte disorder being rectified was 89.5%, the rate of restoring renal function was 66.7% and the total survival rate was 47.6%. In comparison, in the control group the rate of regaining normal consciousness was 16.7%, the rate of electrolyte disorder being rectified was 42.3%, none of their renal functions were restored and the total survival rate was 22.5%. The differences between the two groups were significant (chi2=6.56, P less than 0.05).</p><p><b>CONCLUSION</b>With other medical treatment, combined non-biological artificial liver can improve the survival rate of severe hepatitis patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Liver, Artificial
/
Hepatitis, Chronic
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hepatology
Year:
2006
Type:
Article
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