Antitumor activities of liposoluble components of caulis Marsdeniae tenocissimae and analysis on its chemical constituents / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3325-3328, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-260660
ABSTRACT
<p><b>OBJECTIVE</b>To study the antitumor activities of the liposoluble components from caulis Marsdenia tenocissimae and analyze its chemical constituents.</p><p><b>METHOD</b>The supercritical fluid extraction was used to extract the liposoluble components from caulis M. tenocissimae. MIT test was applied to study the anticancer effects of liposoluble components on growth inhibition in human liver cancer line HepG-2 cells, and the chemical constituents were analyzed by gas chromatography/mass spectrometry (GC-MS).</p><p><b>RESULT</b>The liposoluble components of caulis M. tenocissimae have obvious growth inhibitory action to HepG-2 cells. Twenty-four compounds were identified and their relative contents were determined.</p><p><b>CONCLUSION</b>The liposoluble components from caulis M. tenocissimae have antitumor activities, and its pharmacological activity is related to its chemical constituents.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Solubility
/
Chemistry
/
Marsdenia
/
Cell Proliferation
/
Hep G2 Cells
/
Lipids
/
Gas Chromatography-Mass Spectrometry
/
Antineoplastic Agents
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2010
Type:
Article
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