Inhibitory effect of baicalin on germ tube formation and adhesion of Candida albicans / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3216-3218, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-260717
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of baicalin against Candida albicans germ tube formation, and adherence to buccal epitherial and vaginal epitherial cells.</p><p><b>METHOD</b>Various concentrations of baicalin (100, 50, 10 mg x L(-1)) were incubated with C. albicans suspension, the mixed suspension of C. albicans and human buccal epitherial cells, the mixed suspension of C. albicans and vaginal epitherial cells, respectively. The effects of baicalin on C. albicans germ tube formation, and adherence to buccal epitherial and vaginal epitherial cells were then assessed microscopically.</p><p><b>RESULT</b>All concentrations of baicalin could inhibit C. albicans germ tube formation, and adherent to buccal epitherial and vaginal epitherial cells,while there was no significant difference between standard and clinical strains.</p><p><b>CONCLUSION</b>Baicalin could inhibit C. albicans germ tube formation, and adherence to buccal epitherial and vaginal epitherial cells.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Physiology
/
Vagina
/
Flavonoids
/
Candida albicans
/
Candidiasis
/
Cheek
/
Drug Therapy
/
Epithelial Cells
/
Microbiology
Limits:
Adult
/
Female
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2010
Type:
Article
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