Chemical constituents from roots of Pueraria lobata / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents in the roots of Pueraria lobata.</p><p><b>METHOD</b>Various chromatographic methods were employed to separate of chemical constituents and the spectroscopic methods were used to elucidate the structure.</p><p><b>RESULT</b>Twenty-two compounds were isolated and characterized as beta-sitosterol palmitate (1), beta-sitosterol (2), lupeol (3), lupeone (4) , puerarol (5), diisobutyl phthalate (6), bis(2-ethylhexyl) phthalate (7), sophoracoumestan A (8), coumestrol (9), allantion (10), dadzein (11), formononetin (12), 3'-methoxy daidzein (13), ononin (14), 3'-hydroxy dadzein (15), genistin (16), dadzin (17), 8-methoxy ononin (18), sissotorin (19), (-)-puerol B 2-O-glucopyranoside (20), (6S,9R)-roseoside (21) and sucrose (22), respectively.</p><p><b>CONCLUSION</b>Compounds 1, 5-8, 15, 18, 21 and 22 were isolated from P. lobata for the first time, and componds 1, 5-7, 15, 18, 21 and 22 were isolated from the genus Pueraria for the first time.</p>