Correlation of powder properties and formability of traditional Chinese medicine pellets / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the correlation of powder properties and formability of traditional Chinese medicine pellets prepared by extrusion/spheronization.</p><p><b>METHOD</b>The present effort was designed to evaluate the effects of the characters of powder on pellets formation by extrusion-spheronization, taking Danggui Buxue decoction extracts as a model drug and microcrystalline cellulose (MCC) as an ideal balling material for extrusion-spheronization.</p><p><b>RESULT</b>The diameter of powder had correlation with the plane critical angle of pellets in a certain scope and the sticky coefficient of wet mass affected roundness of pellets.</p><p><b>CONCLUSION</b>Properties of powder have influence on formability of traditional Chinese medicine pellets.</p>