A Case of Glucagonoma Syndrome Diagnosed as Necrolytic Migratory Erythema / 대한피부과학회지
Korean Journal of Dermatology
;
: 856-859, 2005.
Article
in Korean
| WPRIM
| ID: wpr-26130
ABSTRACT
Necrolytic migratory erythema (NME) is a typical cutaneous manifestation of glucagonoma syndrome. The entire syndrome consists of NME, glucose intolerance, weight loss, anemia, glossitis, diarrhea, and increased glucagon levels. We herein report a patient with glucagonoma syndrome who was diagnosed as having NME. A 48-year-old male presented with a 2-month history of painful erythematous, desquamative, erosive papules and plaques on both lower extremities. Histological examination revealed an intraepidermal cleft, the presence of vacuolated, pale epidermal cells, and necrosis in the upper epidermis. His glucagon level was 2650 pg/ml, with the upper limit of a normal range being 250 pg/ml. The patient was treated with octreotide, and showed an improvement of the skin eruption with normalization of the glucagon level within 4 weeks.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reference Values
/
Skin
/
Glucagon
/
Octreotide
/
Weight Loss
/
Glucose Intolerance
/
Lower Extremity
/
Diarrhea
/
Epidermis
/
Necrolytic Migratory Erythema
Type of study:
Diagnostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2005
Type:
Article
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