Allogeneic bone marrow transplantation for the treatment of Bruton disease / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 528-530, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-261388
ABSTRACT
<p><b>OBJECTIVE</b>To explore the efficacy of allogeneic bone marrow transplantation (allo-BMT) for the treatment of Bruton disease.</p><p><b>METHODS</b>HLA-matched sibling bone marrow transplantation was performed for the treatment of 2 cases of X-linked agammaglobulinemia. One of them received allo-BMT twice.</p><p><b>RESULTS</b>Recovery of hematopoiesis was gained at day 20 and day 13 after allo-BMT in the two cases respectively. Serum immunoglobin rose gradually to normal level in three months. Their humoral immuno-system was reconstituted and life quality improved. These two patients are still in disease-free survival for 13 and 2 years respectively. There was no serious graft-versus-host-disease.</p><p><b>CONCLUSION</b>Stem cell transplantation is a choice for the treatment of Bruton disease.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Transplantation, Homologous
/
Blood
/
Hemoglobins
/
Immunoglobulins
/
Bone Marrow Transplantation
/
Treatment Outcome
/
Agammaglobulinemia
/
Leukocyte Count
/
Metabolism
Limits:
Child
/
Child, preschool
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hematology
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS